Monday, December 21, 2009

Best books on aging published this year


Best Books on Aging, Longevity and Life-Extension Studies published this year, 2009.

You are most welcome to add your suggested books here yourself, if you do know some really good new books!


Here is the list of best books on aging, longevity and life-extension studies, which are published this year, 2009. To get more information about these books, just click on the titles below:

Life-Span Extension:
Single-Cell Organisms to Man (Aging Medicine)

by Christian Sell, Antonello Lorenzini, and Holly M. Brown-Borg (Hardcover - Aug 25, 2009)

Book description:
In recent years, remarkable discoveries have been made concerning the underlying mechanisms of aging. In Life-Span Extension: Single-Cell Organisms to Man, the editors bring together a range of illuminating perspectives from researchers investigating the aging process in a variety of species. This novel work addresses the aging process in species ranging from yeast to man and, among other subjects, features detailed discussions of the naked mole-rat, an exceptionally long-lived rodent; the relationship between dietary factors/food restriction and aging; and an evolutionary view of the human aging process.

Single mutations that extend life span have been identified in yeast, worms, flies, and mice, whereas studies in humans have identified potentially important markers for successful aging. At the same time, it has been discovered that the genes and pathways identified in these studies involve a surprisingly small set of conserved functions, most of which have been the focus of aging research for some time. For example, the mTOR pathway, a regulator of translation and protein synthesis, has been identified as a common longevity pathway in yeast and Caenorhabditis elegans. In mammals, this pathway intersects with neuroendocrine pathways and with the insulin/insulin-like growth factor pathways, which have been identified as major modulators of life span and aging in both invertebrates and mice.

Novel, emerging technologies and the increasingly wide variety of systems that are now used to study aging and the mechanisms of aging provide enormous opportunities for the identification of common pathways that modulate longevity. It is these common pathways that are the focus of this important volume.

Epigenetics of Aging
by Trygve O. Tollefsbol (Hardcover - Nov 18, 2009)

Handbook of the Neuroscience of Aging
by Patrick R. Hof and Charles V. Mobbs (Hardcover - Aug 1, 2009)

by John McBrewster, Frederic P. Miller, and Agnes F. Vandome (Paperback - April 24, 2009)

International Handbook of Population Aging
(International Handbooks of Population)

by Peter Uhlenberg (Hardcover - May 28, 2009)

Theoretical studies of aging:
Theoretical studies of aging in biological systems using statistical mechanics and probabilistic approaches

by Diana David-Rus (Paperback - Oct 1, 2009)

Life extension:
Life extension,Senescence,Calorie restriction,Cryonics,Anti-aging,Strategies for Engineered Negligible Senescence

by John McBrewster, Frederic P. Miller, and Agnes F. Vandome (Paperback - Mar 26, 2009)

Transcend: Nine Steps to Living Well Forever
by Ray Kurzweil Ph.D. and Terry Grossman M.D. (Hardcover - April 28, 2009)

Aging: Concepts and Controversies
by Harry R. Moody (Paperback - Mar 4, 2009)

Hormesis: A Revolution in Biology, Toxicology and Medicine
by Mark P. Mattson and Edward J. Calabrese (Hardcover - Nov 18, 2009)

Modelling Longevity Dynamics for Pensions and Annuity Business (Mathematics Texts)
by Ermanno Pitacco, Michel Denuit, Steven Haberman, and Annamaria Olivieri (Hardcover - April 15, 2009)

Longevity, Regeneration, and Optimal Health:
Integrating Eastern and Western Perspectives
(Annals of the New York Academy of Sciences)

by William C. Bushell, Erin L. Olivio, and Neil D. Theise (Paperback - Sep 22, 2009)

Handbook on Immunosenescence:
basic understanding and clinical applications (2 volume set)

by Tamas Fulop, Claudio Franceschi, Katsuiki Hirokawa, and Graham Pawelec (Hardcover - April 7, 2009)

Youth Prolonged: Old Age Postponed
by Robert Weale (Paperback - Dec 15, 2009)

Handbook of Theories of Aging, Second Edition
by Vern L. Bengtson PhD, Daphna Gans PhD, Norella Putney PhD, and Merril Silverstein PhD (Hardcover - Oct 27, 2008)

Living to 100 and Beyond
by Timothy F. Harris (Paperback - April 2009)

If you do know some new really good books that should be added to this list, please feel free to add them here!

Key words:
New books, aging, ageing, longevity, gerontology, gerontological, geriatrics, geriatric, senescence, anti-aging, anti-ageing, rejuvenation, life-extension, immortality

Best books on aging published this year
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Sunday, December 13, 2009

The Future of Aging: Pathways to Human Life Extension

See also:
-- 'Longevity Science' blog
-- 'Health Studies' blog


Here is a new upcoming book for discussion (click on the book title below for more detail):

The Future of Aging: Pathways to Human Life ExtensionEditor-in-chief: Dr. Gregory M. Fahy
Springer, May 4, 2010
Approx. 500 p., Hardcover
ISBN: 978-90-481-3998-9

This new book (about 500 pages) is written by a team of 40 experts.

Book Description provided by the Publisher (Springer):

Just as the health costs of aging threaten to bankrupt developed countries, this book makes the scientific case that a biological "bailout" could be on the way, and that human aging can be different in the future than it is today.

Here 40 authors argue how our improving understanding of the biology of aging and selected technologies should enable the successful use of many different and complementary methods for ameliorating aging, and why such interventions are appropriate based on our current historical, anthropological, philosophical, ethical, evolutionary, and biological context.

Challenging concepts are presented together with in-depth reviews and paradigm-breaking proposals that collectively illustrate the potential for changing aging as never before. The proposals extend from today to a future many decades from now in which the control of aging may become effectively complete.

Examples include sirtuin-modulating pills, new concepts for attacking cardiovascular disease and cancer, mitochondrial rejuvenation, stem cell therapies and regeneration, tissue reconstruction, telomere maintenance, prevention of immunosenescence, extracellular rejuvenation, artificial DNA repair, and full deployment of nanotechnology.

The Future of Aging will make you think about aging differently and is a challenge to all of us to open our eyes to the future therapeutic potential of biogerontology.

Written for:

Biogerontologists and physicians and politicians concerned with issues associated with aging; educated laypeople trying to see the future direction of aging as it may pertain to their own lives; potential use as a teaching tool in graduate level courses about the biology of aging; biomedical research and university libraries that maintain collections related to gerontology.

Key words:
New books, Future of Aging, Life Extension, Greg Fahy, Springer, Aging, Ageing, Gerontology,

Do you have any comments on this new book?
Post them below by clicking here!

Table of contents

Part 1: Introduction and Orientation;

Chapter 1
Bridges to Life
Ray Kurzweil, Kurzweil Technologies, Inc. Wellesley, MA, and Terry Grossman, M.D., Frontier Medical Institute, Denver, CO

Chapter 2
Analyzing Predictions: An Anthropological View of Anti-Aging Futures
Courtney Everts Mykytyn, Ph.D., Department of Anthropology, University of Southern California, Los Angeles, CA, USA

Chapter 3
Towards Naturalistic Transcendence: The Value of Life and Life Extension to Persons as Conative Processes
Steven Horrobin, Ph.D., College of Medicine, University of Edinburgh, Scotland, UK

Chapter 4
The Ethical Basis for Using Human Embryonic Stem Cells in the Treatment of Aging
L. Stephen Coles, M.D., Ph.D., David Geffen School of Medicine, UCLA, Los Angeles, CA, USA

Chapter 5
Evolutionary Origins of Aging
Joshua Mitteldorf, Ph.D., Dept of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ

Chapter 6
Precedents for the Biological Control of Aging: Experimental Postponement, Prevention, and Reversal of Aging Processes
Gregory M. Fahy, Ph.D., Intervene Biomedical, Norco, CA, USA

Part 2: The Future of Aging

Chapter 7
An Approach to Extending Healthspan and Lifespan Today
Chris Heward, Ph.D., President, Kronos Science Laboratory, Phoenix, AZ, USA

Chapter 8
Near-Term Prospects for Amelioration of Cardiovascular Aging
Roger Yu, M.D., Beth Israel Deaconess Medical Center, Boston, MA 02215, and Mohammad Navab, Ph.D., David Geffen School of Medicine, UCLA, Los Angeles, CA, USA

Chapter 9
Near Term Prospects for Broad Spectrum Amelioration of Cancer
Zheng Cui, Ph.D., Wake Forest University School of Medicine, inston-Salem, NC, USA

Chapter 10
Small Molecule Modulators of Sirtuin Activity
Francisco J. Alcain, Ph.D., Robin K. Minor, Ph.D., Jose M. Villalba, Ph.D., Departamento de Biologнa Celular, Fisiologнa e Inmunologнa, Universidad de Cуrdoba, Cуrdoba, Spain, and Rafael de Cabo, Ph.D., Laboratory of Experimental Gerontology, National Institute on Aging, NIH, Baltimore, MD, USA

Chapter 11
Evolutionary Nutrigenomics
Michael Rose, Ph.D., Anthony D. Long, Ph.D., Laurence D. Mueller, Ph.D.,Cristina L. Rizza, Ph.D., Kennedy C. Matsagas, Ph.D.,Lee F. Greer, Ph.D., and Bryant Villeponteau, Ph.D.Genescient, LLC, Irvine, CA, USA

Chapter 12
Biological Effects of Calorie Restriction:Implications for Modification of Human Aging
Stephen R. Spindler, Ph.D., Department of Biochemistry,University of California at Riverside, Riverside, CA, USA

Chapter 13
Calibrating Notch/TGF-Я Signaling for Youthful, Healthy Tissue Maintenance and Repair
Morgan E. Carlson, Ph.D. and Irina M. Conboy, Ph.D., Department of Bioengineering, University of California, Berkeley, CA, USA

Chapter 14
Embryonic Stem Cells:Prospects of Regenerative Medicine for the Treatment of Human Aging
Mike West, Ph.D., Chief Scientific Officer, BioTime, Inc., and Embryome Sciences, Inc., Alameda, CA, USA, and Adjunct Professor, University of California at Berkeley, Berkeley, CA, USA

Chapter 15
Maintenance and Restoration of Immune System Function
Richard Aspinall, Ph.D., and Wayne Mitchell, Ph.D., School of Medicine, Division of Investigative Science,Imperial College London, London, UK

Chapter 16
Mitochondrial Manipulation as a Treatment for Aging
Rafal Smigrodzki, M.D., and Francisco R. Portell, B.S., Gencia, Inc., Charlottesville, VA, USA

Chapter 17
Life Extension by Tissue and Organ Replacement
Anthony Atala, M.D., Director, Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA

Chapter 18
Telomeres and the Arithmetic of Human Longevity
Abraham Aviv, M.D., and John D. Bogden, Ph.D., The Center of Human Development and Aging, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ, USA

Chapter 19
Repairing Extracellular Aging and Glycation
John Furber, C.E.O., Legendary Pharmaceuticals, Inc., Gainesville, FL USA

Chapter 20
Methuselah’s DNA: Defining Genes that Can Extend Longevity
Robert J. Shmookler-Reis, Ph.D., and Joan McEwen, Ph.D. , VA Medical Center, University of Arkansas for Medical Science, Little Rock, AR, USA

Chapter 21
Reversing Age-Related DNA Damage through Engineered DNA Repair
Clifford Steer, M.D., Director, Molecular Gastroenterology Program, and Betsy Kren, Ph.D., Department of Medicine, GI Division, University of Minnesota Medical School, Minneapolis, MN, USA

Chapter 22
WILT: Necessity, Feasibility, Affordability
Aubrey de Grey, Ph.D., Methuselah Foundation, Lorton, VA, USA

Chapter 23
Comprehensive Nanorobotic Control of Human Morbidity and Aging
Robert A. Freitas, Jr., J.D., Institute for Molecular Manufacturing, Palo Alto, CA, USA

Appendices: Two Unusual Potential Sources of Funding for Longevity Research

Appendix I: The SENS Foundation: Accelerating Progress toward Biomedical Rejuvenation, Michael Rae, SENS Foundation, Redwood City, CA, USA

Appendix II: The Manhattan Beach Project, David Kekich, CEO, Maximum Life Foundation, Inc., Los Angeles, CA, USA


The Future of Aging: Pathways to Human Life Extension
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